Infectious Diseases of Poverty

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		Research Article Inferring the potential risks of H7N9 infection by spatiotemporally characterizing bird migration and poultry distribution in eastern China Benyun Shi, Shang Xia, Guo-Jing Yang, Xiao-Nong Zhou, Jiming Liu Infectious Diseases of Poverty 2013, 2:8 (3 May 2013) Abstract \| Provisional PDF \| Editor’s summary In view of the rapid geographic spread and increased number of confirmed cases of novel influenza A(H7N9) virus infections in eastern China, this study develops a model to characterize the impacts of bird migration and poultry distribution on the geographic spread of the infection.
		Research Article Views of health service providers on obstacles to tuberculosis control in Ghana Joshua Amo-Adjei Infectious Diseases of Poverty 2013, 2:9 (2 May 2013) Abstract \| Full text \| PDF \| ePUB \| Editor’s summary The burden of tuberculosis (TB) is more intensive in developing countries, particularly in sub-Saharan Africa. This study explored barriers to TB control in Ghana based on accounts of health service providers. The main barriers identified were untimely release of funds, weak coordination between TB and HIV, weak public-private partnership, and ineffective monitoring and evaluation. Image: Mycobacteria causative agent for pulmonary tuberculosis
		Opinion China’s biggest, most neglected health challenge: Non-communicable diseases Shenglan Tang, John Ehiri, Qian Long Infectious Diseases of Poverty 2013, 2:7 (5 April 2013) Abstract \| Full text \| PDF \| Editor’s summary This article argues that China's ongoing health system reform would provide a unique opportunity to tackle current public health problems if targeted steps were taken to assure that adequate financial and human resources are mapped for effective control and management of NCDs in the country. Image: Fighting against NCDs.
		Research Article Smear positive pulmonary tuberculosis among diabetic patients at the Dessie referral hospital, Northeast Ethiopia Hiwot Amare, Aschalew Gelaw, Belay Anagaw, Baye Gelaw Infectious Diseases of Poverty 2013, 2:6 (27 March 2013) Abstract \| Full text \| PDF \| ePUB \| Editor’s summary The article is all about the impact of the diabetes mellitus on the progression and prevalence pulmonary tuberculosis and how this research finding can be utilised as relevant indicators to monitor pulmonary tuberculosis incidence in diabetic patients. Image: a picture showing the transmission of tuberculosis from an active case to healthy person.
		Research Article In vitro gene silencing of independent phosphoglycerate mutase (iPGM) in the filarial parasite Brugia malayi Prashant Kumar Singh, Susheela Kushwaha, Shahab Mohd, Manisha Pathak, Shailja Misra-Bhattacharya Infectious Diseases of Poverty 2013, 2:5 (25 March 2013) Abstract \| Full text \| PDF \| ePUB \| Editor’s summary In the current study siRNA were used to silence the independent phosphoglycerate mutase gene to observe the biological role of iPGM in B. malayi viability, female worm embryogenesis and establishment of infection in the host. Infective larvae treated with Bm-iPGM specific siRNA were inoculated into the peritoneal cavity of jirds to study the effect of siRNA treatment on in vivo larval development. Image: Female Brugia malayi worm, causative agent of lymphatic filariasis
		Opinion Time to tackle clonorchiasis in China Men-Bao Qian, Ying-Dan Chen, Fei Yan Infectious Diseases of Poverty 2013, 2:4 (19 February 2013) Abstract \| Full text \| PDF \| Editor’s summary To further demonstrate the threat of clonorchiasis to public health in China, this paper compares it with hepatitis B. Additionally, major problems and prioritized research are discussed. Image: Global distribution of liver fluke infections.
		Research Article On the exoneration of Dr. William H. Stewart: debunking an urban legend Brad Spellberg, Bonnie Taylor-Blake Infectious Diseases of Poverty 2013, 2:3 (18 February 2013) Abstract \| Full text \| PDF \| Editor’s summary It is time to close the book on infectious diseases, and declare the war against pestilence won - One of the most infamous quotes in the history of biomedicine, long attributed to the United States Surgeon General, Dr. William H. Stewart (1965-1969), is now shown to be an urban legend with origins in legitimate public health policy. Image: It is from 1965, and shows William Stewart as Surgeon General on the far left, with President Johnson in the middle, and NIH Director Dr. James Shannon on the right.
		Scoping Review Epidemiology and interactions of Human Immunodeficiency Virus – 1 and Schistosoma mansoni in sub-Saharan Africa Humphrey D Mazigo, Fred Nuwaha, Shona Wilson, Safari M Kinung'hi, Domenica Morona, Rebecca Waihenya, Jorg Heukelbach, David W Dunne Infectious Diseases of Poverty 2013, 2:2 (24 January 2013) Abstract \| Full text \| PDF \| Editor’s summary The fishing communities of Africa remain at higher risk of acquiring both infections and co-infections. The available evidence indicates that immunological interactions of the two diseases in single human host are associated with severe morbidities. Image: Fishermen at Kayenze village, one of the fishing villages on the southern shore of the Lake Victoria, north-western Tanzania.
		Editorial Elimination of tropical disease through surveillance and response Xiao-Nong Zhou, Robert Bergquist, Marcel Tanner Infectious Diseases of Poverty 2013, 2:1 (3 January 2013) Abstract \| Full text \| PDF \| Editor’s summary It is recommended that the surveillance-response systems to take place in two different stages corralling the basic components of the surveillance-response system for NTD elimination in developing countries, based on the innovative and effective One world-One health perspective to detect, report, analyze, interpret and take action. Image: taking surveillance of zoonotic diseases.
		Research Article Assessing the impact of TB/HIV services integration on TB treatment outcomes and their relevance in TB/HIV monitoring in Ghana Gloria Akosua Ansa, John D Walley, Kamran Siddiqi, Xiaolin Wei Infectious Diseases of Poverty 2012, 1:13 (24 December 2012) Abstract \| Full text \| PDF \| Editor’s summary The article describes the impact of the integration of TB and HIV services on TB treatment outcomes, and how these outcomes can be utilised as relevant indicators to monitor the effectiveness of the integration. Image: A graph comparing number of TB patients dying, after integration of TB and HIV services, who are HIV-positive or negative.
		Research Article Providing financial incentives to rural-to-urban tuberculosis migrants in Shanghai: an intervention study Xiaolin Wei, Guanyang Zou, Jia Yin, John Walley, Huaixia Yang, Merav Kliner, Jian Mei Infectious Diseases of Poverty 2012, 1:9 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary This article reports the effectiveness of providing financial incentives to migrant TB patients, especially the poor migrants on the treatment completion and default rates in one district of Shanghai. Image: Residency of rural-to-urban migrants.
		Opinion Schistosomiasis control and the health system in P.R. China Charles Collins, Jing Xu, Shenglan Tang Infectious Diseases of Poverty 2012, 1:8 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary The health system offers a positive environment for the control of schistosomiasis from grass-roots level in P.R. China. Agencies for schistosomiasis control have abandoned the function of medical treatment and are still independent from the CDC system in areas where schistosomiasis is not under control. Image: One agency for schistosomiasis control at county level.
		Scoping Review Scaling up impact of malaria control programmes: a tale of events in Sub-Saharan Africa and People’s Republic of China Ernest Tambo, Ahmed Adedeji, Fang Huang, Jun-Hu Chen, Shui-Sen Zhou, Ling-Hua Tang Infectious Diseases of Poverty 2012, 1:7 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary This systematic review provides scientific evidence on the trends in malaria events 1960 - 2011, as well as the achievements, progress and challenges in research, through informed decisions on public health issues and intervention designs towards elimination in both Africa and China. Image: The malaria incidence patterns of selective African countries and China.
		Opinion Health systems perspectives – infectious diseases of poverty Dale Huntington Infectious Diseases of Poverty 2012, 1:12 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary A health systems framework is applied to the articles in the inaugural issue of the new journal: Infectious Diseases of Poverty. Many of the articles discuss treatments and delivery strategies. A recommendation for future editions is to explore other health system components to increase understanding of effective and sustainable interventions to reduce the burden of infectious disease among the poor. Image: Reaching remote populations.
		Scoping Review Malaria transmission modelling: a network perspective Jiming Liu, Bo Yang, William K Cheung, Guojing Yang Infectious Diseases of Poverty 2012, 1:11 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary The network approach enables public health authorities and epidemiologists to gain insights into the impact of disease transmission over time and space, and the underlying factors such as environment and human mobility. Image: Approach for the inferring malaria transmission network
		Research Article Association between water related factors and active trachoma in Hai district, Northern Tanzania Michael J Mahande, Humphrey D Mazigo, Eliningaya J Kweka Infectious Diseases of Poverty 2012, 1:10 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary This study was conducted to assess the association of water related factors, general hygiene and active trachoma among preschool and school age children in Hai district, northern Tanzania. Image: A Masai woman with a baby both infested with flies on their faces.
		Research Article Socio-cultural determinants of timely and delayed treatment of Buruli ulcer: Implications for disease control Mercy M Ackumey, Margaret Gyapong, Matilda Pappoe, Cynthia Maclean, Mitchell G Weiss Infectious Diseases of Poverty 2012, 1:6 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary An integrated approach to Buruli ulcer that includes periodic screening for early case-detection, collaboration with private practitioners and traditional healers and, use of mobile services to improve access, adherence and treatment outcomes is suggested.
		Research Article Infectious disease emergence and global change: thinking systemically in a shrinking world Colin D Butler Infectious Diseases of Poverty 2012, 1:5 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary Global environmental change threatens to worsen emerging infectious diseases through rising food prices and deteriorating health governance; better care for the planet and its creatures will help to protect human health.
		Scoping Review The global epidemiology of clonorchiasis and its relation with cholangiocarcinoma Men-Bao Qian, Ying-Dan Chen, Song Liang, Guo-Jing Yang, Xiao-Nong Zhou Infectious Diseases of Poverty 2012, 1:4 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary To promote awareness of the importance of clonorchiasis, this Review examines the global epidemiology status and characteristics, as well as the relationship between Clonorchis sinensis infection and cholangiocarcinoma. Image: Raw freshwater fish causing clonorchiasis.
		Commentary Control of neglected tropical diseases in Asia Pacific: implications for health information priorities Robert Bergquist, Maxine Whittaker Infectious Diseases of Poverty 2012, 1:3 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary Bergquist and Whittaker discuss the unique role of informatics platforms in supporting neglected tropical disease control and elimination programmes in the Asia Pacific region. Image: A pig was roaming around human habitat with rubbish.
		Opinion Technology innovation for infectious diseases in the developing world Anthony D So, Quentin Ruiz-Esparza Infectious Diseases of Poverty 2012, 1:2 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary The gulf between R&D investments and the burden of diseases of poverty has precipitated the need for new forms of innovation: from evolving collaborative norms to alternative R&D financing models. Image: Mapping out a framework of innovation for global health.
		Editorial Prioritizing research for “One health - One world” Xiao-Nong Zhou Infectious Diseases of Poverty 2012, 1:1 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary There are three components in the logo: (1) the worm (that looks like a schistosome) makes reference to infectious diseases; (2) the distorted house around the worm represents poverty and environmental challenges; (3) the whole shape of the logo resembles an old time seal meaning that infectious diseases of poverty are an ancient and persisting public health problem that we need to tackle through innovation. Image: Logo of Infectious Diseases of Poverty

	All
		Research Article Inferring the potential risks of H7N9 infection by spatiotemporally characterizing bird migration and poultry distribution in eastern China Benyun Shi, Shang Xia, Guo-Jing Yang, Xiao-Nong Zhou, Jiming Liu Infectious Diseases of Poverty 2013, 2:8 (3 May 2013) Abstract \| Provisional PDF \| Editor’s summary In view of the rapid geographic spread and increased number of confirmed cases of novel influenza A(H7N9) virus infections in eastern China, this study develops a model to characterize the impacts of bird migration and poultry distribution on the geographic spread of the infection.
		Research Article Views of health service providers on obstacles to tuberculosis control in Ghana Joshua Amo-Adjei Infectious Diseases of Poverty 2013, 2:9 (2 May 2013) Abstract \| Full text \| PDF \| ePUB \| Editor’s summary The burden of tuberculosis (TB) is more intensive in developing countries, particularly in sub-Saharan Africa. This study explored barriers to TB control in Ghana based on accounts of health service providers. The main barriers identified were untimely release of funds, weak coordination between TB and HIV, weak public-private partnership, and ineffective monitoring and evaluation. Image: Mycobacteria causative agent for pulmonary tuberculosis
		Opinion China’s biggest, most neglected health challenge: Non-communicable diseases Shenglan Tang, John Ehiri, Qian Long Infectious Diseases of Poverty 2013, 2:7 (5 April 2013) Abstract \| Full text \| PDF \| Editor’s summary This article argues that China's ongoing health system reform would provide a unique opportunity to tackle current public health problems if targeted steps were taken to assure that adequate financial and human resources are mapped for effective control and management of NCDs in the country. Image: Fighting against NCDs.
		Research Article Smear positive pulmonary tuberculosis among diabetic patients at the Dessie referral hospital, Northeast Ethiopia Hiwot Amare, Aschalew Gelaw, Belay Anagaw, Baye Gelaw Infectious Diseases of Poverty 2013, 2:6 (27 March 2013) Abstract \| Full text \| PDF \| ePUB \| Editor’s summary The article is all about the impact of the diabetes mellitus on the progression and prevalence pulmonary tuberculosis and how this research finding can be utilised as relevant indicators to monitor pulmonary tuberculosis incidence in diabetic patients. Image: a picture showing the transmission of tuberculosis from an active case to healthy person.
		Research Article In vitro gene silencing of independent phosphoglycerate mutase (iPGM) in the filarial parasite Brugia malayi Prashant Kumar Singh, Susheela Kushwaha, Shahab Mohd, Manisha Pathak, Shailja Misra-Bhattacharya Infectious Diseases of Poverty 2013, 2:5 (25 March 2013) Abstract \| Full text \| PDF \| ePUB \| Editor’s summary In the current study siRNA were used to silence the independent phosphoglycerate mutase gene to observe the biological role of iPGM in B. malayi viability, female worm embryogenesis and establishment of infection in the host. Infective larvae treated with Bm-iPGM specific siRNA were inoculated into the peritoneal cavity of jirds to study the effect of siRNA treatment on in vivo larval development. Image: Female Brugia malayi worm, causative agent of lymphatic filariasis
		Opinion Time to tackle clonorchiasis in China Men-Bao Qian, Ying-Dan Chen, Fei Yan Infectious Diseases of Poverty 2013, 2:4 (19 February 2013) Abstract \| Full text \| PDF \| Editor’s summary To further demonstrate the threat of clonorchiasis to public health in China, this paper compares it with hepatitis B. Additionally, major problems and prioritized research are discussed. Image: Global distribution of liver fluke infections.
		Research Article On the exoneration of Dr. William H. Stewart: debunking an urban legend Brad Spellberg, Bonnie Taylor-Blake Infectious Diseases of Poverty 2013, 2:3 (18 February 2013) Abstract \| Full text \| PDF \| Editor’s summary It is time to close the book on infectious diseases, and declare the war against pestilence won - One of the most infamous quotes in the history of biomedicine, long attributed to the United States Surgeon General, Dr. William H. Stewart (1965-1969), is now shown to be an urban legend with origins in legitimate public health policy. Image: It is from 1965, and shows William Stewart as Surgeon General on the far left, with President Johnson in the middle, and NIH Director Dr. James Shannon on the right.
		Scoping Review Epidemiology and interactions of Human Immunodeficiency Virus – 1 and Schistosoma mansoni in sub-Saharan Africa Humphrey D Mazigo, Fred Nuwaha, Shona Wilson, Safari M Kinung'hi, Domenica Morona, Rebecca Waihenya, Jorg Heukelbach, David W Dunne Infectious Diseases of Poverty 2013, 2:2 (24 January 2013) Abstract \| Full text \| PDF \| Editor’s summary The fishing communities of Africa remain at higher risk of acquiring both infections and co-infections. The available evidence indicates that immunological interactions of the two diseases in single human host are associated with severe morbidities. Image: Fishermen at Kayenze village, one of the fishing villages on the southern shore of the Lake Victoria, north-western Tanzania.
		Editorial Elimination of tropical disease through surveillance and response Xiao-Nong Zhou, Robert Bergquist, Marcel Tanner Infectious Diseases of Poverty 2013, 2:1 (3 January 2013) Abstract \| Full text \| PDF \| Editor’s summary It is recommended that the surveillance-response systems to take place in two different stages corralling the basic components of the surveillance-response system for NTD elimination in developing countries, based on the innovative and effective One world-One health perspective to detect, report, analyze, interpret and take action. Image: taking surveillance of zoonotic diseases.
		Research Article Assessing the impact of TB/HIV services integration on TB treatment outcomes and their relevance in TB/HIV monitoring in Ghana Gloria Akosua Ansa, John D Walley, Kamran Siddiqi, Xiaolin Wei Infectious Diseases of Poverty 2012, 1:13 (24 December 2012) Abstract \| Full text \| PDF \| Editor’s summary The article describes the impact of the integration of TB and HIV services on TB treatment outcomes, and how these outcomes can be utilised as relevant indicators to monitor the effectiveness of the integration. Image: A graph comparing number of TB patients dying, after integration of TB and HIV services, who are HIV-positive or negative.
		Research Article Providing financial incentives to rural-to-urban tuberculosis migrants in Shanghai: an intervention study Xiaolin Wei, Guanyang Zou, Jia Yin, John Walley, Huaixia Yang, Merav Kliner, Jian Mei Infectious Diseases of Poverty 2012, 1:9 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary This article reports the effectiveness of providing financial incentives to migrant TB patients, especially the poor migrants on the treatment completion and default rates in one district of Shanghai. Image: Residency of rural-to-urban migrants.
		Opinion Schistosomiasis control and the health system in P.R. China Charles Collins, Jing Xu, Shenglan Tang Infectious Diseases of Poverty 2012, 1:8 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary The health system offers a positive environment for the control of schistosomiasis from grass-roots level in P.R. China. Agencies for schistosomiasis control have abandoned the function of medical treatment and are still independent from the CDC system in areas where schistosomiasis is not under control. Image: One agency for schistosomiasis control at county level.
		Scoping Review Scaling up impact of malaria control programmes: a tale of events in Sub-Saharan Africa and People’s Republic of China Ernest Tambo, Ahmed Adedeji, Fang Huang, Jun-Hu Chen, Shui-Sen Zhou, Ling-Hua Tang Infectious Diseases of Poverty 2012, 1:7 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary This systematic review provides scientific evidence on the trends in malaria events 1960 - 2011, as well as the achievements, progress and challenges in research, through informed decisions on public health issues and intervention designs towards elimination in both Africa and China. Image: The malaria incidence patterns of selective African countries and China.
		Opinion Health systems perspectives – infectious diseases of poverty Dale Huntington Infectious Diseases of Poverty 2012, 1:12 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary A health systems framework is applied to the articles in the inaugural issue of the new journal: Infectious Diseases of Poverty. Many of the articles discuss treatments and delivery strategies. A recommendation for future editions is to explore other health system components to increase understanding of effective and sustainable interventions to reduce the burden of infectious disease among the poor. Image: Reaching remote populations.
		Scoping Review Malaria transmission modelling: a network perspective Jiming Liu, Bo Yang, William K Cheung, Guojing Yang Infectious Diseases of Poverty 2012, 1:11 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary The network approach enables public health authorities and epidemiologists to gain insights into the impact of disease transmission over time and space, and the underlying factors such as environment and human mobility. Image: Approach for the inferring malaria transmission network
		Research Article Association between water related factors and active trachoma in Hai district, Northern Tanzania Michael J Mahande, Humphrey D Mazigo, Eliningaya J Kweka Infectious Diseases of Poverty 2012, 1:10 (1 November 2012) Abstract \| Full text \| PDF \| Editor’s summary This study was conducted to assess the association of water related factors, general hygiene and active trachoma among preschool and school age children in Hai district, northern Tanzania. Image: A Masai woman with a baby both infested with flies on their faces.
		Research Article Socio-cultural determinants of timely and delayed treatment of Buruli ulcer: Implications for disease control Mercy M Ackumey, Margaret Gyapong, Matilda Pappoe, Cynthia Maclean, Mitchell G Weiss Infectious Diseases of Poverty 2012, 1:6 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary An integrated approach to Buruli ulcer that includes periodic screening for early case-detection, collaboration with private practitioners and traditional healers and, use of mobile services to improve access, adherence and treatment outcomes is suggested.
		Research Article Infectious disease emergence and global change: thinking systemically in a shrinking world Colin D Butler Infectious Diseases of Poverty 2012, 1:5 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary Global environmental change threatens to worsen emerging infectious diseases through rising food prices and deteriorating health governance; better care for the planet and its creatures will help to protect human health.
		Scoping Review The global epidemiology of clonorchiasis and its relation with cholangiocarcinoma Men-Bao Qian, Ying-Dan Chen, Song Liang, Guo-Jing Yang, Xiao-Nong Zhou Infectious Diseases of Poverty 2012, 1:4 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary To promote awareness of the importance of clonorchiasis, this Review examines the global epidemiology status and characteristics, as well as the relationship between Clonorchis sinensis infection and cholangiocarcinoma. Image: Raw freshwater fish causing clonorchiasis.
		Commentary Control of neglected tropical diseases in Asia Pacific: implications for health information priorities Robert Bergquist, Maxine Whittaker Infectious Diseases of Poverty 2012, 1:3 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary Bergquist and Whittaker discuss the unique role of informatics platforms in supporting neglected tropical disease control and elimination programmes in the Asia Pacific region. Image: A pig was roaming around human habitat with rubbish.
		Opinion Technology innovation for infectious diseases in the developing world Anthony D So, Quentin Ruiz-Esparza Infectious Diseases of Poverty 2012, 1:2 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary The gulf between R&D investments and the burden of diseases of poverty has precipitated the need for new forms of innovation: from evolving collaborative norms to alternative R&D financing models. Image: Mapping out a framework of innovation for global health.
		Editorial Prioritizing research for “One health - One world” Xiao-Nong Zhou Infectious Diseases of Poverty 2012, 1:1 (25 October 2012) Abstract \| Full text \| PDF \| Editor’s summary There are three components in the logo: (1) the worm (that looks like a schistosome) makes reference to infectious diseases; (2) the distorted house around the worm represents poverty and environmental challenges; (3) the whole shape of the logo resembles an old time seal meaning that infectious diseases of poverty are an ancient and persisting public health problem that we need to tackle through innovation. Image: Logo of Infectious Diseases of Poverty